Cocaine-associated plasma cell orificial mucositis is a rare condition diagnosed in cocaine users who present with exudative ulcerated plaques within the nostrils. These lesions appear between 2 and 24 months following cocaine intake. Patients may present with other findings associated with cocaine use, such as septal perforation. Histologically, there are abundant polyclonal plasma cell infiltrates with rare eosinophils.
This is a newly identified entity with only about 10 cases reported to date.
Cocaine-associated plasma cell orificial mucositis
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Synopsis
Codes
ICD10CM:
J34.81 – Nasal mucositis (ulcerative)
T40.5X5S – Adverse effect of cocaine, sequela
SNOMEDCT:
292181009 – Cocaine adverse reaction
36669007 – Ulcerative nasal mucositis
J34.81 – Nasal mucositis (ulcerative)
T40.5X5S – Adverse effect of cocaine, sequela
SNOMEDCT:
292181009 – Cocaine adverse reaction
36669007 – Ulcerative nasal mucositis
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Last Reviewed:03/02/2025
Last Updated:03/03/2025
Last Updated:03/03/2025