Contributors: Keith Sweitzer MD, Danielle Wilbur MD
               
            
               
               
            
              
               Synopsis
               
               
               Classic history and presentation: Intrinsic plus hand is a posture characterized by metacarpophalangeal (MCP) flexion with proximal interphalangeal (PIP) and distal interphalangeal (DIP) extension. This is caused by an imbalance between spastic intrinsic and weak extrinsic muscles of the hand. In early cases, patients complain of difficulty with gripping large objects. Later, the patient may develop contractures and lose the ability to extend their fingers at the MCP joint or flex at the IP joints.
Prevalence: Intrinsic plus hand is not more prevalent in any particular age group, nor is it more common in patients of any particular sex.
Risk factors: 
Pathophysiology:
- Spastic intrinsic muscles lead to MCP joint flexion and IP joint extension.
- Flexor digitorum superficialis (FDS) and flexor digitorum profundus (FDP) weakness fail to provide the balancing flexion force to PIP and DIP joints.
- Extensor digitorum communis (EDC) weakness fails to provide the balancing extension force to the MCP joint.
 
            
            
               
               Codes
               
               
                  ICD10CM:
M24.549 – Contracture, unspecified hand
SNOMEDCT:
86414002 – Contracture of joint of hand
            
               
               Differential Diagnosis & Pitfalls
               
               
                     
                         
                        To perform a comparison, select diagnoses from the classic differential
                      
                   
               
            
               Last Reviewed:10/01/2022
               Last Updated:03/28/2024